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MSSI Article Features on Journal Cover

Biological Chemistry Biological Chemistry

An article published by MSSI researchers, Professor Tewfik Soulimane and Dr Mohamed Noor, was featured on the cover page of Biological Chemistry (Noor, M. R. and T. Soulimane. May 2013. Structure of caa3 Cytochrome cOxidase – A Nature-made Enzyme-substrate Complex. Biological Chemistry, 394 (5), pp. 579-591. ISSN:1431-6730). Crystallisation of membrane proteins represents the bottleneck for their X-ray structural analysis. This article describes an optimised protocol for the generation of single crystals of caa3-oxidase – the enzyme responsible for cellular oxygen reduction - which has been subsequently used for structural comparison across different types of enzymes